Document Type : Original Article
Authors
1
Anesthesia, Intensive Care & Pain Management, Faculty of Medicine, New Valley University, Egypt.
2
Anesthesia, Intensive Care & Pain Management, Faculty of Medicine, Assiut University, Assiut, Egypt.
3
Gynecological and Obstetric, Faculty of Medicine, Assiut University, Assiut, Egypt.
4
House officer of AL-Azhar University, Faculty of Medicine, Assiut University, Assiut, Egypt.
Abstract
Background: The Quadratus Lumborum Block (QLB) effectively provides postoperative analgesia. In this study, we sought to demonstrate the impact of adding Midazolam to the Quadratus Lumborum Block on the 24-hour total dosage of ketorolac, 1st VAS in the first 24 hours, initial analgesia required, and duration of analgesia after cesarean section [1, 2].
Methods: Forty-two female patients who underwent cesarean sections were included in this research.
The study group got 41 ml (40 ml bupivacaine 0.25% with 5 mg midazolam in 1 ml) divided on each side.
We assessed the amount of ketorolac consumed over 24 hours, the VAS score, and the time for the first analgesia request (for ketorolac).
Results:
Forty-two participants participated in this double-blinded, prospective, controlled randomized clinical study.
Compared to the control group, the study group's VAS decreased significantly at rest and during movement (2,4,8, and 12 hours) with a p-value < 0.0001. Compared to the control group (10.43 ± 1.75) hours, the study group had a substantial delay in their initial analgesic demand (15.48 ± 1.75) hours. The ketorolac dosages were significantly lower in the midazolam group (35.45 ± 11.8 mg) compared to the control group (55.7 ± 10.7mg).
Discussion:
Posterior QLB reduces postoperative pain following cesarean surgery. Midazolam reduces ketorolac dosages, the VAS score, and the initial rescue analgesia when added to PQLB.
Keywords
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