Epidemiology of Acute Kidney Injury in Diabetic Patients Infected with COVID-19 in Assiut University Hospital

Document Type : Original Article

Authors

1 Departments of Internal Medicine,Faculty of Medicine,Assiut University.

2 Departments of Chest, Faculty of Medicine, Assiut University.

Abstract

Background: Across numerous investigations, diabetes has emerged as a prominently reported comorbidity associated with unfavorable prognosis in patients with COVID-19. Furthermore, a substantial proportion of critically ill patients are prone to the development of acute kidney injury (AKI) at some point during their intensive care unit (ICU) admission.
Objectives: To study the epidemiology of AKI in diabetic patients infected with COVID-19 infection compared to non-diabetic cases admitted to ICU.
Patients and Methods: This study is a retrospective cross-sectional study performed at the ICU in quarantine at Assiut University Hospital from the first of March 2021 to the end of March 2022. This study includes two groups of patients: non-diabetic COVID patients with AKI and diabetic COVID patients with AKI.
Results: The study included 90 COVID-19-infected patients (38 were non-diabetic (42.2%), and 52 cases (57.8%) were diabetic. There was a statistically significant reduction among the studied groups regarding comparing kidney function tests among non-diabetic individuals with COVID-19 over time. ROC curve for AKI prediction by APACHE II score with the area under the curve = 0.638 (0.52 to 0.75), the best cut-off point 15.5, Sensitivity 66.7%, Specificity 62.7%, and P value = 0.026.
Conclusion: AKI is one of the main complications among COVID-19-infected individuals, regardless of the presence of other risk factors such as diabetes and/or hypertension.

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