Analgesic effect of nulbuphine-bupivacaine combination in ultrasound guided Transversus abdominis plane block in patients undergoing major abdominal cancer surgeries.

Document Type : Original Article

Authors

1 department of Anesthesia,Intensive Care and pain management ,South Egypt Cancer Institute ,Assiut University,

2 department of Anesthesia ,Intensive care and pain management, Assiut University,

Abstract

Analgesic effect of nulbuphine-bupivacaine combination in ultrasound guided Transversus abdominis plane block in patients undergoing major abdominal cancer surgeries.

Abstract:

Background:
TAP block is considered a modality of pain management following major abdominal cancer surgeries. In this study, we are trying to determine whether the addition of nalbuphine in two different doses as an adjunct to bupivacaine in transversus abdominis plane block confers better post-major abdominal cancer surgery pain management or not.
Methods:

Ninety patients scheduled for major abdominal cancer surgeries were randomly allocated to one of three groups. Group (B) received a TAP block with bupivacaine only, group (N10) received a TAP block with bupivacaine and 10 mg nalbuphine, and group (N20) received a TAP block with bupivacaine and 20 mg nalbuphine. Our primary outcome was the time of the first request for rescue analgesia. The secondary outcomes were total morphine consumption in the first postoperative 24 hours, postoperative VAS scores, Spirometric lung functions (FEV1, FVC, and FEV1/FVC), and postoperative side effects.
Results:

There is a significant difference between group (B), group (N10), and group (N20) in the 1st request of analgesia and the total amount of morphine, VAS score, and respiratory function. However, there is no significance between the three groups in hemodynamics and side effects.
Conclusion:

Nulbuphine added to bupivacaine in TAP block has advantages over bupivacaine only more pain relief less analgesic request and less total amount of morphine in patients undergoing cancer abdominal surgeries in a dose-dependent manner.

Keywords

Files

Share

How to cite

Statistics