Abstract: Background
Dense breasts represent a risk factor for breast cancer, but unfortunately, they represent a weak point in conventional digital mammography (DM) interpretation due to tissue overlapping and increased conspicuity of the lesion; hence, the development of digital tomosynthesis (DBT) came to overcome this obstacle, allowing better characterization of lesions, reducing patient recall and medical costs. Objectives: To assess the impact of DBT on the interpretation of dense breasts and its advantages and disadvantages over DM, hence estimate its role in dense breast screening. Method: Eighty-three patients with dense breasts (ACR C or D) were included in our study, either having detectable lesions or indeterminate findings by Ultrasound (US) and DM, over 12 months between November 2022 and October 2023.
All patients underwent DM and DBT, which were correlated to histopathology and/ or follow-up. Results: DBT exhibited a higher sensitivity, specificity, accuracy, PPV, and NPV than DM, with moderate kappa agreement (k=0.4115). Conclusions: DBT improved the identification and characterization of diverse dense breast abnormalities with much
Sayed Hassan, A., Abdelmonem Ahmed, A., Abo Elhamed Ahmed, E., Zidan Mohamed, M., & Mohamed Fouad Mahmoud, D. (2025). Impact of Using Digital Breast Tomosynthesis on the Interpretation of Dense Breasts. Journal of Current Medical Research and Practice, 10(4), 169-178. doi: 10.21608/jcmrp.2025.372123.1251
MLA
Alzahraa Sayed Hassan; Asmaa Abdelmonem Ahmed; Eman Abo Elhamed Ahmed; Mohamed Zidan Mohamed; Doaa Mohamed Fouad Mahmoud. "Impact of Using Digital Breast Tomosynthesis on the Interpretation of Dense Breasts", Journal of Current Medical Research and Practice, 10, 4, 2025, 169-178. doi: 10.21608/jcmrp.2025.372123.1251
HARVARD
Sayed Hassan, A., Abdelmonem Ahmed, A., Abo Elhamed Ahmed, E., Zidan Mohamed, M., Mohamed Fouad Mahmoud, D. (2025). 'Impact of Using Digital Breast Tomosynthesis on the Interpretation of Dense Breasts', Journal of Current Medical Research and Practice, 10(4), pp. 169-178. doi: 10.21608/jcmrp.2025.372123.1251
VANCOUVER
Sayed Hassan, A., Abdelmonem Ahmed, A., Abo Elhamed Ahmed, E., Zidan Mohamed, M., Mohamed Fouad Mahmoud, D. Impact of Using Digital Breast Tomosynthesis on the Interpretation of Dense Breasts. Journal of Current Medical Research and Practice, 2025; 10(4): 169-178. doi: 10.21608/jcmrp.2025.372123.1251